abstract：OBJECTIVE:To report our findings from a sample of narcoleptic children and adolescents evaluated in our unit from 1988 to 2005. PATIENTS AND METHODS:The sample was composed of nine children (5 boys) with a mean age of 14.5 years at diagnosis. The protocol included the following: Epworth, Ullanlinna narcolepsy scale, a...

journal_title：Sleep medicine

authors： Peraita-Adrados R,García-Peñas JJ,Ruiz-Falcó L,Gutiérrez-Solana L,López-Esteban P,Vicario JL,Miano S,Aparicio-Meix M,Martinez-Sopena MJ

更新日期：2011-01-01 00:00:00

abstract：:We present a case of violent sleep-related behaviour in a patient with narcolepsy with cataplexy (NC) and REM sleep behaviour disorder (RBD), causing injuries to his wife that resulted in charge of assault, followed by a divorce case. This observation pinpoints that RBD in NC can arise early in a patient's life and th...

journal_title：Sleep medicine

authors： Ingravallo F,Schenck CH,Plazzi G

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy of moderate aerobic physical activity with sleep hygiene education to improve sleep, mood and quality of life in older adults with chronic insomnia. METHODS:Seventeen sedentary adults aged >or=55 years with insomnia (mean age 61.6 [SD±4.3] years; 16 female) participated in a randomized...

journal_title：Sleep medicine

authors： Reid KJ,Baron KG,Lu B,Naylor E,Wolfe L,Zee PC

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To investigate cortical excitability in patients with obstructive sleep apnea syndrome (OSAS) during wakefulness. METHODS:The authors recruited 45 untreated severe OSAS (all males, mean age 47.2 years, mean apnea-hypopnea index=44.6h(-1)) patients and 44 age-matched healthy male volunteers (mean apnea-hypopn...

journal_title：Sleep medicine

authors： Joo EY,Kim HJ,Lim YH,Koo DL,Hong SB

更新日期：2010-10-01 00:00:00

abstract：INTRODUCTION:Sleep restriction and sleep disorders are common causes of excessive daytime sleepiness (EDS). Medical disorders (MD) can also cause EDS, but previous studies have used non-standardized measures, selected samples, or have examined EDS in singular disorders. This study describes the relative degree of EDS a...

journal_title：Sleep medicine

authors： Stroe AF,Roth T,Jefferson C,Hudgel DW,Roehrs T,Moss K,Drake CL

更新日期：2010-10-01 00:00:00

abstract：PURPOSE:To produce a valid insomnia treatment satisfaction questionnaire (ITSAT-Q) to assess treatment satisfaction with pharmacotherapy for use in patients with insomnia. PATIENTS AND METHODS:Items developed for a self-administered questionnaire were analyzed using exploratory factor analysis (EFA), which produced 5 ...

journal_title：Sleep medicine

authors： Beyer AP,Szeinbach SL,Seoane-Vazquez EC,Gliem JA,Doan J,Wal GS,Lichstein KL

更新日期：2010-09-01 00:00:00

abstract：:Children and adolescents with autistic spectrum disorders (ASD) suffer from sleep problems, particularly insomnia, at a higher rate than typically developing children, ranging from 40% to 80%. Sleep problems in ASD might occur as a result of complex interactions between biological, psychological, social/environmental,...

journal_title：Sleep medicine

authors： Cortesi F,Giannotti F,Ivanenko A,Johnson K

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVES:This study aimed to evaluate children's bedtime, wake-up time, total sleep duration (TSD), sleep latency, and daytime napping by age and gender. Its secondary aim was to compare sleep duration among demographic and lifestyle factors. METHODS:We performed a cross-sectional study of 3639 children in Daegu, Ko...

journal_title：Sleep medicine

authors： Seo WS,Sung HM,Lee JH,Koo BH,Kim MJ,Kim SY,Choi SJ,Shin IH

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:Ramelteon, an MT(1)/MT(2) melatonin receptor agonist, was evaluated for its ability to reduce sleep-onset difficulties associated with eastward jet travel. METHODS:Healthy adults (n=110) with a history of jet lag sleep disturbances were flown eastward across five time zones from Hawaii to the east coast of t...

journal_title：Sleep medicine

authors： Zee PC,Wang-Weigand S,Wright KP Jr,Peng X,Roth T

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVES:The aims of this research were to estimate prevalence of insomnia, describe the utilization patterns of physician office services and prescription medications for insomnia, and estimate related costs in a Medicaid population. METHODS:A cross-sectional descriptive analysis using data from the West Virginia (...

journal_title：Sleep medicine

authors： Roy AN,Smith M

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:Pulse wave attenuation, which occurs in association with obstructive sleep apnea (OSA), is sympathetically mediated. We compared the effect of Doxazosin (DO, a peripheral alpha-receptor inhibitor) and Enalapril (EN, an ACE inhibitor) on digital vasoconstriction and nocturnal blood pressure (BP) in hypertensiv...

journal_title：Sleep medicine

authors： Zou D,Grote L,Eder DN,Radlinski J,Hedner J

更新日期：2010-03-01 00:00:00

abstract：STUDY OBJECTIVES:Few commercially available brands of actigraphs (ACT) have been subjected to rigorous validation with infant participants. The purpose of this study was to examine the agreement between concurrent polysomnography (PSG) and one brand of ACT (AW-64, Mitter Co. Inc.) using appropriate statistical techniqu...

journal_title：Sleep medicine

authors： Insana SP,Gozal D,Montgomery-Downs HE

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Depression is a common problem in patients with Delayed Sleep Phase Syndrome (DSPS). This study used a randomized, double-blind, crossover, placebo-controlled approach to test the hypothesis that exogenous melatonin (5mg) can attenuate depressive symptomatology in DSPS patients. METHODS:Twenty patients with...

journal_title：Sleep medicine

authors： Rahman SA,Kayumov L,Shapiro CM

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:Two doses of EVT 201, a partial positive allosteric modulator of the GABA(A) system, were evaluated in elderly primary insomnia patients with daytime sleepiness. PATIENTS AND METHODS:Participants were 149 elderly patients with DSM-IV primary insomnia including evidence of daytime sleepiness (53 males, 96 fem...

journal_title：Sleep medicine

authors： Walsh JK,Salkeld L,Knowles LJ,Tasker T,Hunneyball IM

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To determine if patients with autonomic failure have increased sleep disturbances and if multiple system atrophy (MSA) and pure autonomic failure (PAF) patients have frequent arousals from sleep associated with an attenuated heart rate (HR) response compared to healthy volunteers. METHODS:With informed conse...

journal_title：Sleep medicine

authors： Freilich S,Goff EA,Malaweera AS,Twigg GL,Simonds AK,Mathias CJ,Morrell MJ

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:This study aimed at determining the mean total sleep time (TST) and the relationship between sleep duration and basic socio-demographic factors and BMI sleep problems in Chinese subjects. METHOD:A total of 5926 subjects were randomly selected and interviewed using standardized assessment tools. RESULTS:The ...

journal_title：Sleep medicine

authors： Xiang YT,Ma X,Lu JY,Cai ZJ,Li SR,Xiang YQ,Guo HL,Hou YZ,Li ZB,Li ZJ,Tao YF,Dang WM,Wu XM,Deng J,Lai KY,Ungvari GS

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Patients with obstructive sleep apnea syndrome (OSAS) are known to have an increased risk for motor vehicle crashes. They suffer from sleep-related respiratory abnormality causing repetitive arousal leading to daytime sleepiness. In turn, it has been demonstrated that sleepiness can impair human psychomotor ...

journal_title：Sleep medicine

authors： Stoohs RA,Philip P,Andries D,Finlayson EV,Guilleminault C

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:The mechanisms involved in sleep perception are not widely known. Therefore, we believe that investigating this phenomenon is the best way to understand some of the mechanisms involved in several sleep disturbances, particularly insomnias. OBJECTIVE:The objective of our study was to evaluate sleep perceptio...

journal_title：Sleep medicine

authors： Pinto LR Jr,Pinto MC,Goulart LI,Truksinas E,Rossi MV,Morin CM,Tufik S

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND AND AIM:Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) is associated with glucose dysmetabolism and insulin resistance, therefore the amelioration of breathing disturbances during sleep can allegedly modify the levels of markers of glucose regulation and insulin resistance, such as glycated hemoglobin, fa...

journal_title：Sleep medicine

authors： Steiropoulos P,Papanas N,Nena E,Tsara V,Fitili C,Tzouvelekis A,Christaki P,Maltezos E,Bouros D

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:To examine the long-term relationship between sleep duration and type 2 diabetes or impaired glucose tolerance (IGT). METHODS:Body composition measurements and self-reported sleep duration were determined in a longitudinal sample of 276 individuals aged 21 to 64 years followed for a mean of 6 years. Risk fac...

journal_title：Sleep medicine

authors： Chaput JP,Després JP,Bouchard C,Astrup A,Tremblay A

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:To examine the associations between sleep hygiene and sleep patterns in children ages newborn to 10 years. The relationships between key features of good sleep hygiene in childhood and recognizable outcomes have not been studied in large, nationally representative samples. PARTICIPANTS AND METHODS:A national...

journal_title：Sleep medicine

authors： Mindell JA,Meltzer LJ,Carskadon MA,Chervin RD

更新日期：2009-08-01 00:00:00

abstract：:Sixteen percent of adults ultimately diagnosed with having narcolepsy/cataplexy experienced symptoms before the age of ten years, 4.5% even before the age of five years. The symptomatology in childhood narcolepsy/cataplexy can differ significantly from adults and can lead to misinterpretations and misdiagnosis. Standa...

journal_title：Sleep medicine

authors： Dhondt K,Verhelst H,Pevernagie D,Slap F,Van Coster R

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:To evaluate the efficacy and safety profile of gaboxadol, a selective extrasynaptic GABA(A) agonist (SEGA) previously in development for the treatment of insomnia. METHODS:This was a randomised, double-blind, placebo-controlled, parallel-group, 2-week, Phase III study of gaboxadol 5, 10 and 15mg in outpatie...

journal_title：Sleep medicine

authors： Hajak G,Hedner J,Eglin M,Loft H,Stórustovu SI,Lütolf S,Lundahl J,Gaboxadol Study 99775 Group.

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Sleep-disordered breathing (SDB) is more prevalent in stroke patients than age- and sex-matched controls, but the relationship between SDB and functional outcome of stroke patients is unclear. The aim of our study was to determine the prevalence of SDB in ischemic stroke and its influence on func...

journal_title：Sleep medicine

authors： Yan-fang S,Yu-ping W

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Very few prospective studies examine the relationship between childhood sleep problems and subsequent substance use. In this study, we examined how sleep problems at ages 3-8 predicted onset of alcohol, cigarette, and marijuana use in adolescence. We also investigated the relationships between childhood slee...

journal_title：Sleep medicine

authors： Wong MM,Brower KJ,Zucker RA

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:To examine personality characteristics as potential mediators of the association between Restless Legs Syndrome (RLS) and psychiatric disorders. METHOD:Revised NEO Personality Inventory traits are compared in respondents with (n=42) versus without (n=982) a diagnosis of RLS in a general population sample. R...

journal_title：Sleep medicine

authors： Kalaydjian A,Bienvenu OJ,Hening WA,Allen RP,Eaton WW,Lee HB

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to prospectively examine all patients with a diagnosis of RLS consulting a sleep disorders clinic and to assess RLS severity and augmentation and their associations, including ferritin levels. METHODS:Patients were stratified into patients with RLS as ancillary diagnosis, RLS suffer...

journal_title：Sleep medicine

authors： Frauscher B,Gschliesser V,Brandauer E,El-Demerdash E,Kaneider M,Rücker L,Poewe W,Högl B

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:New simplified techniques for diagnosing sleep apnea should be specially tailored for easy use in cardiologic practice. OBJECTIVES:e dedicated one of the channels of a Holter Electrocardiogram (ECG) device (SpiderView() ELA Medical, France) to nasal pressure (NP) recordings. We also developed an automatic a...

journal_title：Sleep medicine

authors： Pépin JL,Defaye P,Vincent E,Christophle-Boulard S,Tamisier R,Lévy P

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:To evaluate, both polysomnographically and by subjective scales, the efficacy and safety profile of pramipexole for restless legs syndrome (RLS) via a 3-week, double-blind, placebo-controlled, parallel-group, dose-ranging study. METHODS:At baseline and after 3 weeks, periodic limb movements (PLM) and sleep p...

journal_title：Sleep medicine

authors： Jama L,Hirvonen K,Partinen M,Alakuijala A,Hublin C,Tamminen I,Koester J,Reess J

更新日期：2009-06-01 00:00:00

abstract：:We report a new, pathologically verified Italian case of fatal familial insomnia, whose clinical presentation was characterised by complex behavioural disturbances, suggesting wakefulness/NREM/REM combinations. ...

journal_title：Sleep medicine

authors： Raggi A,Perani D,Giaccone G,Iannaccone S,Manconi M,Zucconi M,Garibotto V,Marcone A,Zamboni M,Limido L,Tagliavini F,Ferini-Strambi L,Cappa SF

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Relatively few epidemiologic studies have focused on narcolepsy, a disabling sleep disorder with a strong association with HLA-DQB1 *0602. METHODS:We sought to estimate the prevalence of narcolepsy using multiple overlapping techniques to identify residents of King County, WA who were 18 years or older with...

journal_title：Sleep medicine

authors： Longstreth WT Jr,Ton TG,Koepsell T,Gersuk VH,Hendrickson A,Velde S

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To document and provide a micro analysis of the relationship between insomnia and health problems, health-care use, absenteeism, productivity and accidents. PARTICIPANTS AND METHODS:A population-based sample of 953 French-speaking adults from Québec, Canada. Participants were categorized as havi...

journal_title：Sleep medicine

authors： Daley M,Morin CM,LeBlanc M,Grégoire JP,Savard J,Baillargeon L

更新日期：2009-04-01 00:00:00

abstract：INTRODUCTION:Sleep apnea-hypopnea syndrome (SAHS) is an emerging disease with high prevalence. There is controversy as to whether cardiac abnormalities are due to the disease itself or to the arterial hypertension frequently associated with this disease. OBJECTIVES:To analyze echocardiographic abnormalities in a popul...

journal_title：Sleep medicine

authors： Moro JA,Almenar L,Fernández-Fabrellas E,Ponce S,Blanquer R,Salvador A

更新日期：2009-03-01 00:00:00

abstract：:Rapid eye movement (REM) sleep behavior disorder (RBD) is frequently seen in patients with neurodegenerative diseases. It can also be seen in brainstem lesions involving the pons. However, RBD in patients with a pure pontine infarction has been rarely reported. A 68-year-old man had a two-month history of violent beha...

journal_title：Sleep medicine

authors： Xi Z,Luning W

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to investigate the demographic variables and clinical characteristics of behaviorally induced insufficient sleep syndrome (BIISS) and to compare it with the other major hypersomnia disorders. PATIENTS AND METHODS:One-thousand two-hundred forty-three consecutive patients...

journal_title：Sleep medicine

authors： Komada Y,Inoue Y,Hayashida K,Nakajima T,Honda M,Takahashi K

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Contradictory data have been published on the influence of Apolipoprotein E (APOE) epsilon4 allele on obstructive sleep apnea (OSA). The aims of this study were to confirm the presence of specific neuropsychological changes in OSA patients carrying the APOE epsilon4 allele and to clarify if these changes are...

journal_title：Sleep medicine

authors： Cosentino FI,Bosco P,Drago V,Prestianni G,Lanuzza B,Iero I,Tripodi M,Spada RS,Toscano G,Caraci F,Ferri R

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Rare are the studies that focus on OSAS (obstructive sleep apnoea syndrome) obese patient assessing neuropsychological, psychological and clinical aspects simultaneously. METHODS:One hundred and fifty-seven obese patients with OSAS were psychologically and neuropsychologically assessed by a standardized bat...

journal_title：Sleep medicine

authors： Pierobon A,Giardini A,Fanfulla F,Callegari S,Majani G

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Using transcranial B-mode sonography (TCS), the first morphological marker for restless legs syndrome (RLS), hypoechogenicity of the substantia nigra (SN) has been found. The aim of this study was to validate SN hypoechogenicity as a morphological marker for RLS in a large patient cohort and to i...

journal_title：Sleep medicine

authors： Godau J,Wevers AK,Gaenslen A,Di Santo A,Liepelt I,Gasser T,Berg D

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Continuous positive airway pressure (CPAP) is an effective treatment for sleep apnea (SA), although the evidence for improving chronic heart failure (CHF) is inconclusive. Our aim was to evaluate the effect of CPAP treatment on the left ventricle ejection fraction (LVEF) among other cardiological...

journal_title：Sleep medicine

authors： Egea CJ,Aizpuru F,Pinto JA,Ayuela JM,Ballester E,Zamarrón C,Sojo A,Montserrat JM,Barbe F,Alonso-Gomez AM,Rubio R,Lobo JL,Duran-Cantolla J,Zorrilla V,Nuñez R,Cortés J,Jiménez A,Cifrián J,Ortega M,Carpizo R,Sánchez

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea (OSA) and asthma are common and share similar nocturnal symptoms. We hypothesized that the prevalence of OSA symptoms would be greater in asthmatics compared to a general internal medicine population. METHODS:Patients in the Asthma Clinics (n=177) and Internal Medicine Clinics (n=328...

journal_title：Sleep medicine

authors： Auckley D,Moallem M,Shaman Z,Mustafa M

更新日期：2008-07-01 00:00:00